Mouth Ulcers Research Today is a free monthly online journal that collates and summarizes the latest research about Mouth Ulcers, including details on treatment, causes, medication, remedies.

Ecstasy (MDMA) and oral health.

Brand HS, Dun SN, Nieuw Amerongen AV

Department of Dental Basic Sciences, Section of Oral Biochemistry, Centre for Dentistry Amsterdam (ACTA), Amsterdam, the Netherlands. hs.brand@vumc.nl

3,4-methylenedioxymethamphetamine (MDMA), more commonly known as 'ecstasy' or XTC, is frequently used by young adults in the major cities. Therefore, it is likely that dentists might be confronted with individuals who use ecstasy. This review describes systemic and oral effects of ecstasy. Life-threatening complications include hyperthermia, hyponatraemia and liver failure. In addition, psychotic episodes, depression, panic disorders and impulsive behaviour have been reported. Oral effects include xerostomia, bruxism, and an increased risk of developing dental erosion. Mucosal changes have also been reported. Recent use of ecstasy may interfere with dental treatment. Finally, the potential use of saliva for non-invasive detection of ecstasy is discussed.

Published 12 February 2008 in Br Dent J, 204(2): 77-81.
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